The Center of Biomedical Research Excellence (COBRE) in Membrane Protein Production and Characterization at the University of Delaware was established in 2000 with generous support under the COBRE program within the National Center for Research Resources (NCRR) of the National Institutes of Health (NIH). Additional support was provided by the Delaware Biotechnology Institute (DBI). Support was renewed in 2005, with the program more narrowly focused on membrane protein production and characterization. Additional information on projects and facilities will be available soon.