CHEMICAL & BIOMOLECULAR ENGINEERING

People

Faculty

Yun Liu

Yun Liu
  • Research Associate Professor

NIST
University of Delaware
Newark, Delaware 19716
yunliu@udel.edu
302-831-301-975-6235
302-831-301-921-9847 (fax)


Education
  • Doctorate - 2005 MIT
  • Masters - 1999 Tsinghua University
  • Bachelors - 1997 Tsinghua University

"The rapid development of novel nano-scale materials makes it necessary to understand these advanced materials at the molecular scale. This requires developing a fundamental relationship between the structure and physical properties as the dimensions of a system are reduced. Our interests are to develop a comprehensive and detailed knowledge to then establish the relations between the material performance and the dynamics and structure. We utilize scattering tools, such as neutron/x-ray/light scattering, in conjunction with advanced mathematical modeling to understand both the structure and dynamics of materials. Our strong relationship with the NIST Center for Neutron Research gives us access to their state of the art neutron scattering instruments.

Current research interests include:

1. Particle interactions in bio-colloidal systems
Unlike simple liquids, colloidal solutions are intrinsically complex due to the presence of different components, such as ions and solvent molecules. However, this complexity makes it possible to modify the effective interaction between colloidal particles at will, allowing one to obtain a variety of macroscopic behaviors. It is this tunability that makes colloidal systems so important in our everyday lives. Furthermore, the collective behavior of colloidal systems also plays a fundamental role in processes such as protein crystallization, viscosity changes, gelation, and glass transitions.

2. Properties of materials confined in nano-scale structures
Although storing and releasing molecules in porous media is an old topic, it has been increasingly important nowadays due to applications such as energy storage and drug delivery. This renewed interest has led to many newly developed porous materials, such as porous crystals and open colloidal particles. When molecules are confined in porous nano-structures, the confined materials often demonstrate new properties, very different from those of the bulk material. These new properties are not only important for real applications, but also interesting to serve as test beds to explore fundamental scientific principles."

XSelected Publications

For a complete listing of publications, please view the Full CV.
  1. P. Douglas Godfrin, Steven D. Hudson, Kunlun Hong, Lionel Porcar, Peter Falus, Norman J. Wagner, Yun Liu, "Short-time glassy dynamics in viscous protein solutions with competing interactions", Phys. Rev. Lett. 115, 228302, (2015)
  2. Jie Chen, Steven Kline, Yun Liu, "From the depletion attraction to the bridging attraction: the effect of solvent molecules on the effective colloidal interactions", J. of Chem. Phys. 142, 084904, (2015)
  3. P. Douglas Godfrin, Nestor E. Valadez-Perez, Ramon Castaneda-Priego, Norman J. Wagner, Yun Liu, "Generalized phase behavior of cluster formation in colloidal dispersions with competing interactions", Soft Matter 10, 5061, (2014)
  4. Eric J. Yearley, Paul D. Godfrin, Tatiana Perevozchikova, Hailiang Zhang, Peter Falus, Lionel Porcar, Michihiro Nagao, Joseph E. Curtis, Pradad Gawande, Rosalynn Taing, Isidro E. Zarraga, Norman J. Wagner, "Observation of small cluster formation in concentrated monoclonal antibody solutions and its implications to solution viscosity", Biophysical Journal 106, 1763, (2014)
  5. Y. Liu*, L. Porcar, J. Chen, W. R. Chen, P. Falus, A. Faraone, E. Fratini, K. Hong, P. Baglioni, "Lysozyme Protein Solution with an Intermediate Range Order Structure", J. Phys. Chem. B 115, 7238, (2011)
  6. L. Porcar, P. Falus, W. R. Chen, A. Faraone, E. Fratini, K. Hong, P. Baglioni, Y. Liu, "Formation of the Dynamic Clusters in Concentrated Lysozyme Protein Solutions", J. of Physical Chemistry Letters 1, 126, (2010)
  7. Xiang, W. Zhou, J. M. Gallegos, Y. Liu*, B. Chen, "Exceptionally High Acetylene Uptake in a Microporous Metal-Organic Framework with Open Metal Sites", J. of the American Chemical Society 131, 12415, (2009)
  8. Y. Liu, H. Kabbour, C. M. Brown, D. A. Neumann, C. C. Ahn, "Increasing the Density of Adsorbed Hydrogen with Coordinatively Unsaturated Metal Centers in Metal-organic Frameworks", Langmuir 24, 4772, (2008)
  9. M. Dinca, A. Dailly, Y. Liu, C. M. Brown, D. A. Neumann, J. R. Long, "Hydrogen Storage in a Microporous Metal-Organic Framework with Exposed Mn2+ Coordination Sites", J. of the American Chemical Society 128, 16876, (2006)
  10. Y. Liu, W. R. Chen, S. H. Chen, "Cluster Formation in Two Yukawa Fluids", J. of Chemical Physics 122, (2005)

XPatents

XSelected Awards

For a complete listing of awards, please view the Full CV.
  1. Neutron Scattering Society of America Science Prize for "the discovery of dynamic cluster ordering in complex colloidal and protein systems using neutron scattering": 2016
  2. Distinguished referee of The European Physical Journal: 2015
  3. Katherine B. Gebbie Young Scientist Award for "the contributions to the field of soft matter, in particular, to fundamental colloid science and its application to biopharmaceutical science" (NIST-Sigma Xi: 2014)
  4. Outstanding Poster Award (NIST chapter of Sigma Xi: 2008)
  5. Shanghai Laser Award for Research Achievement, Nuclear Science and Engineering Department (MIT: 2005)
  6. Presidential Fellowship (MIT: 2002)


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