CHEMICAL & BIOMOLECULAR ENGINEERING

People

Faculty

April Kloxin

April Kloxin
  • Assistant Professor
  • Joint Professor, Materials Science

207 CLB
University of Delaware
Newark, Delaware 19716
AKLOXIN@UDEL.EDU
302-831-3009
302-831-1048 (fax)


Education
  • Doctorate - 2009 University of Colorado at Boulder
  • Masters - 2004 North Carolina State University
  • Bachelors - 2001 North Carolina State University

"To meet the need for complex, dynamic cell culture environments, we are developing materials with highly controlled properties for spatiotemporal regulation of the cell niche and utilizing biological techniques to characterize and exploit these materials for cell culture and tissue regeneration. We aim to control material structure and properties on multiple time scales and size scales to probe and direct cell function."

XSelected Publications

For a complete listing of publications, please view the Full CV.
  1. LA Sawicki, AM Kloxin, "Design of thiol-ene photoclick hydrogels using facile techniques for cell culture applications", Biomaterials Science - DOI: 10.1039/c4bm00187g 2, 1612, (2014)
  2. PM Kharkar, AM Kloxin, KL Kiick, "Dually degradable click hydrogels for controlled degradation and protein release,", Journal of Materials Chemistry B - DOI: 10.1039/C4TB00496E 2, 5511, (2014)
  3. ME Smithmyer, LA Sawicki, AM Kloxin, "Hydrogel scaffolds as in vitro models to study fibroblast activation in wound healing and disease", Biomaterials Science - DOI: 10.1039/C3BM60319A 2, 634, (2014)
  4. PM Kharkar, KL Kiick, AM Kloxin, "Designing hydrogels for orthogonal control of degradable cell microenvironments", Chemical Society Reviews - DOI: 10.1039/C3CS60040H 42, 7335, (2013)
  5. MS Rehmann, AM Kloxin, "Tunable and dynamic soft materials for three-dimensional cell culture", Soft Matter, In Press (Advance Article) (2013)
  6. DD McKinnon, AM Kloxin, KS Anseth, "Synthetic hydrogel platform for three-dimensional culture of embryonic stem cell-derived motor neurons", Biomaterials Science - DOI: 10.1039/C3BM00166K 1, 460, (2013)
  7. AM Kloxin, KJR Lewis, CA DeForest, MW Tibbitt, V Balasubramaniam, and KS Anseth, "Responsive culture platform to examine the influence of microenvironmental geometry on cell function in 3D", Integrative Biology - DOI: 10.1039/C2IB20212C 4, 1540, (2012)
  8. AM Kloxin, MW Tibbitt and KS Anseth, "Synthesis of photodegradable hydrogels as dynamically tunable cell culture platforms", Nature Protocols 5, 1867, (2010)
  9. AM Kloxin, JA Benton, and KS Anseth, "In situ elasticity modulation with dynamic substrates to direct cell phenotype", Biomaterials 33, 1, (2010)
  10. AM Kloxin, AM Kasko, CN Salinas, and KS Anseth, "Photolabile hydrogels for dynamic tuning of physical and chemical properties", Science 324, 59, (2009)

XPatents

XSelected Awards

For a complete listing of awards, please view the Full CV.
  1. NASA Graduate Student Research Program Fellowship: 2005 - 2008
  2. US Department of Education?s GAANN Fellowship: 2005 - 2009
  3. Excellence in Graduate Polymer Research Award, ACS POLY Division
  4. Max S. Peters Outstanding Graduate Research Award
  5. National Science Foundation CAREER Award
  6. Burroughs Wellcome Fund Grant & UC-Davis Visiting Scholar
  7. Western Association of Graduate Schools Innovation in Technology Award


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