Aditya M. Kunjapur

Aditya Kunjapur
  • Assistant Professor

University of Delaware
Newark, Delaware 19716
302-831-1048 (fax)

  • Post-Doctorate - 2018 Harvard Medical School
  • Doctorate - 2015 Massachusetts Institute of Technology
  • Bachelors - 2010 University of Texas at Austin

"The goal of our lab is to use synthetic biology approaches to investigate how microbes can use non-standard chemistry and unusual building blocks to generate products that exhibit enhanced functionality. Products of interest include fuels, chemicals, materials, and therapeutics.

Example questions of interest are: What useful functional groups can we generate on small molecules and proteins using enzymatic catalysis and metabolic engineering? Will small molecules containing unusual functional groups be orthogonal to endogenous cellular processes, will they be consumed by the cell, or will they be toxic? Will these molecules be able to enter/exit cells? How might we engineer cells to overcome potential challenges with orthogonality, toxicity, or transport? Can we use non-standard amino acid incorporation to advance rational modification of enzyme active sites and protein binding pockets? Advancements in synthetic biology, genome engineering, and intelligent screening enable us to efficiently determine answers to these questions."

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