Erik Welf
Ph.D. 2003 - , University of Delaware
B.S. Chemical Engineering 1998-2002, North Carolina State University
B.S. Paper Science and Engineering 1998-2002, North Carolina State University
(302) 831-0726
Research Interests
I am working with computational and experimental methods to investigate the cell signaling components relevant to cell adhesion and migration, with the aim of developing therapies for a variety of diseases, including cancer and cardiovascular disease. Taking a systems approach to understanding cell signaling allows us to model and interpret cell behavior so that we can recommend therapies which consider holistic integration of a biological system's different parts. Specifically, we are investigating how the integrin family of adhesive proteins function as part of a signaling network to regulate cell migration and motility. This is in collaboration with Dr. Ulhas P. Naik, Dept. of Biological Sciences, as part of the IGERT program. Please access the “research statement” document above for more information regarding my personal research interests and philosophy.
Publications
Erik S. Welf, Ulhas P. Naik, Babatunde A. Ogunnaike, A Diffusion-Reaction Model for Integrin Clustering, J. R.. Soc. Interface. In preparation.
Erik S. Welf, Ulhas P. Naik, Babatunde A. Ogunnaike, A Control Engineering Model for Hemostasis Following Blood Vessel Injury. In preparation.
Erik S. Welf, Ulhas P. Naik, Babatunde A. Ogunnaike, Computational Insight into Integrin Regulation of Cell Migration. In preparation.
Erik S. Welf, Ulhas P. Naik, Babatunde A. Ogunnaike, Regulation of Integrin Cluster Size: Experiments and Models. In preparation.
Erik S. Welf, Ulhas P. Naik, Babatunde A. Ogunnaike, Feedback Between a Phosphoinositide Kinase and Talin Provide a Possible Mechanism for Integrin Clustering. In Preparation.
Erik S. Welf, Richard A. Venditti, Martin A. Hubbe, and Joel J. Pawlak. The effects of heating without water removal and drying on the swelling as measured by water retention value and degradation as measured by intrinsic viscosity of cellulose papermaking fibers. Progress in Paper Recycling 2005; 14 (3): 1-9.
Erik S. Welf, Richard A. Venditti, Hasan Jameel, and Jean J. Renard. Pulping wax-containing old corrugated containers with hardwood chips in a Kraft pulping operation. Progress in Paper Recycling 2003; 12 (2): 13-18.
Erik Welf and Richard A. Venditti, The effect of the chemical structure of agglomerating agents on toner agglomeration for deinking. Progress in Paper Recycling 2001; 10 (2): 24-34.
Conference Presentations
Computational Investigation of How Integrin Clustering Affects Cell Adhesion and Migration, Erik S. Welf, Ulhas P. Naik, Babatunde A. Ogunnaike, AIChE Annual Meeting, Philadelphia PA, November 16-21, 2008 November 16-21, 2008
A Control Engineering Model for Hemostasis Following Blood Vessel Injury, Erik S. Welf, Ulhas P. Naik, Babatunde A. Ogunnaike, AIChE Annual Meeting, Philadelphia PA, November 16-21, 2008
A Diffusion-Reaction Model for Integrin Clustering, Erik S. Welf, Ulhas P. Naik, and Babatunde A. Ogunnaike. Presented at the 2007 Foundations of Systems Biology in Engineering, Stuttgart, Germany September 9-12 2007.
A Diffusion-Reaction Model for Integrin Clustering in Response to Cell Adhesion, AIChE Annual Meeting, Cincinnati, OH, October 30-November 2004.
"The Effect of Surfactant Structure on Toner Agglomeration", E. S. Welf and R. A. Venditti, Golden Key International Honour Society International Conference, Dallas, Texas, August 2001
Poster Presentations
Experimental Investigation of the Relationship Between Integrin Clustering and Focal Adhesion Kinase Phosphorylation, AIChE Annual Meeting, Philadelphia PA, November 16-21, 2008.
Computational Modeling and Experimental Quantitation of Focal Adhesion Formation in Endothelial Cells, Presented at the 2006 AIChE Annual Meeting, San Francisco, CA, November 12-17.
A Diffusion-Reaction Model for Platelet Integrin aIIbb3 Clustering, Presented at the 33rd Annual Philadelphia Workshop on Hemostasis, Thrombosis, and Arteriosclerosis, Philadelphia PA, November 2005.
"The Effects of Paper Processing on Wood Fibers", E. S. Welf , R. A. Venditti, M. A. Hubbe, 2001 TAPPI Pulping Conference, Seattle WA.
"The Effect of Heating and Drying on the Properties of Recycled Papermaking Fibers", E. Welf and R. A. Venditti, The Tenth Annual North Carolina State University Undergraduate Research Symposium, Book of Abstracts, pg. 71, 2001.
"The Effect of Surfactant Structure on Toner Agglomeration" E. Welf and R. A. Venditti, The Ninth Annual North Carolina State University Undergraduate Research Symposium, Book of Abstracts, pg. 81, 2000.
Home l Research l People l Publications l ChE Home
Last update: 01/29/2007
Copyright © 2004. The Ogunnaike Group. All Rights Reserved.