University of Delaware - College of Engineering



Wilfred Chen

Wilfred Chen
  • Gore Professor of Chemical Engineering

224 CLB
University of Delaware
Newark, Delaware 19716
302-831-1048 (fax)

  • Doctorate - 1993 California Institute of Technology
  • Bachelors - 1988 University of California, Los Angeles

"The complex interactions between humans and the biosphere have created some of our most challenging global problems in human history such as energy sustainability, environmental pollutions, and emergence or re-emergence of old and new epidemics and diseases. Research in my laboratory is focused on development of the next generation biomolecular tools in addressing these key global problems in viral infection, disease pathogenesis, biofuel production, and separation of protein pharmaceutics."

XSelected Publications

For a complete listing of publications, please view the Full CV.
  1. Shen-Long Tsai, Nancy A. DaSilva, and Wilfred Chen, "Functional display of complex cellulosomes on the yeast surface via adaptive assembly", ACS Synthetic Biology 0
  2. Garima Goyal, Shen Long Stai, Bhawna Madan, Nancy A. DaSilva and Wilfred Chen, "Simultaneous cell growth and ethanol production from cellulose by engineered yeast consortium displaying a functional mini-cellulosome", Microbial Cell Factories 10, 89, (2011)
  3. Payal Ganguli, Wilfred Chen, and Marylynn V. Yates, "Detection of Murine Norovirus-1 using TAT peptide delivered molecular beacon", Appl. Environ Microbiol 77, 5517, (2011)
  4. Payal Biswas, Lakshmi N Cella, Seung Hyun Kang, Ashok Mulchandani, Marylynn V. Yates and Wilfred Chen, "A quantum-dot based protein module for in vivo monitoring of protease activity through fluorescence resonance energy transfer", Chemical Communications 47, 5259, (2011)
  5. Hsiao-Yun Yeh, Marylynn V. Yates, Ashok Mulchandani and Wilfred Chen, "Molecular beacon-quantum dot-Au nanoparticle hybrid nanoprobes for visualizing virus replication in living cells", Chemical Communications 46, 3914, (2010)
  6. Shen-Long Tsai, Jeongseok Oh, Shailendra Singh, Ruizhen Chen and Wilfred Chen, "Functional assembly of mini-cellulosomes on the yeast surface for cellulose hydrolysis and ethanol production", Applied and Environmental Microbiology 75, 6087, (2009)
  7. Hsiao-Yun Yeh, Maryynn V. Yates, Ashok Mulchandani and Wilfred Chen, "Visualizing the dynamics of viral replication in living cells via TAT-peptide delivery of nuclease-resistant molecular beacons", Proc. Natl. Acad. Sci. USA 105, 17522, (2008)
  8. Seung Hyun Kang, Krassimir N. Bozhilov, Nosang V. Myung, Ashok Mulchandani and Wilfred Chen, "Microbial synthesis of CdS nanocrystals in genetically engineered E. coli", Angewandte Chemie International Edition 47, 5186, (2008)
  9. Shailendra Singh, Ashok Mulchandani and Wilfred Chen, "Highly selective and rapid arsenic removal by metabolically engineered E. coli expressing Fucus vesiculosus metallothionein", Appl. Environ. Microbiol 74, 2924, (2008)
  10. U Loi Lao, Minwei Sun, Mark Matsumoto, Ashok Mulchandani, and Wilfred Chen, "Genetic engineering of self-assembled protein hydrogel based on elastin-like sequences with metal binding functionality", Biomacromolecules 8, 3736, (2007)


XSelected Awards

For a complete listing of awards, please view the Full CV.
  1. Gore Professor of Chemical Engineering: 2011
  2. Fellows, American Institute for Medical and Biological Engineering (AIMBE): 2011
  3. AIChE Food, Pharmaceutical, and Bioengineering Division Plenary Session, Biochemical Engineering (Area 15c) Award: 2008
  4. UC Presidential Chair: 2006 - 2010
  5. Fellows, American Association for the Advancement of Science: 2006
  6. Invited Participant of the Fifth Annual U.S./Japan Frontiers of Engineering Symposum: 2005
  7. Invited Participant of the National Academy of Engineering's Fourth Annual Symposium on Frontiers of Engineering: 1998
  8. NSF Faculty Early Career Development Award: 1997

Bookmark and Share